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Brand: | Hitachi Japan |
ChromasterUltra
Rs, an ultra-high performance liquid chromatograph, provides the ultimate in
high performance, high resolution, and high sensitivity analysis that are
becoming requirements for research and development in pharmaceutical and
chemical fields.
High
Resolution
The
newly developed LaChromUltra II column is the longest UHPLC column at 250 mm in
length. When used together with the reduced volume system ChromasterUltra Rs,
it produces an exceptional high-separation performance.
*EachEach
column has its own recommended flow rate range for analysis, and it is
advisable to abide by these limits in order to maintain and optimize the
separation performance of any column.
The
combination of this column and the ChromasterUltra Rs enables system pressure
tolerance of 140 MPa with 50,000 or more theoretical plates per column.
High
Sensitivity
A
total-reflection capillary flow cell is incorporated into the diode array
detector to answer to the increasing need for high-sensitivity analysis of
hazardous substances, genotoxic impurities, etc. A high-sensitivity flow cell
with an optical path length of 65 mm is also available. In addition to the
capability of high-sensitivity analysis, carryover is reduced through the use
of a double-corkscrew mixer.
High-sensitivity
total-reflection capillary flow cell
The
diode array detector (DAD) exhibits low noise and low drift, achieved through
the use of a new optical system providing optimal conditions for
high-sensitivity analysis. The optional high-sensitivity flow cell (optical
path length of 65 mm) further enhances sensitivity; about a tenfold increase is
obtained compared with our previous model (LaChromUltra), thus enabling
high-sensitivity applications including impurities from side reactions,
genotoxic impurities, etc.
The
acquisition of impurity profiles during all stages of synthesis and in raw
materials used in medicines and chemicals, intermediate byproducts, and
finished drugs are examples of useful applications.
Double-corkscrew
mixer
The
binary pump is equipped with the latest design in microfluidic double-corkscrew
mixers.
An efficient mixing is attained even for a low volume, resulting in a baseline
that is extremely stable during gradient analysis, enabling higher-sensitivity
analysis.
Structure
of the double-corkscrew mixer:
Repeated branching and merging of channels within the mixer provide effective
solvent mixing (mixer volume of 55 µL).
Column |
LaChromUltra II C18(1.9 µm)
2.0 mm I.D.×50 mm L. |
Eluent |
A)0.1% TFA/H2O(v/v) |
Flow rate |
0.500 mL/min |
Detection |
UV 214 nm |
Carryover
Low
carryover (0.001% or less) is attained via the optimized injection port
structure.
All
modules can be controlled from the Graphical User Interface (GUI) controller.
The GUI is comprised of a color LCD monitor (5.7-inch color TFT display with
LED back-light) and a touch panel made for easy viewing and simple operation.
Up to 10 programs including a timer function, pre-analysis tasks (Wakeup), and
post-analysis tasks (Sleep) can be created for a system.
The GUI controller enables you to check the status of consumables usage for all
units that are connected to the system.
MEM
Column fitting (optional)
Hitachi'
s own Moment Enhancing Mechanism (MEM) column fitting is a simple but exciting
new development. The finger-tight piping integral fitting, which has a very
small dead volume, is capable of safely tolerating system pressures as high as
140 MPa.
Get specific details about this product from customers who own it.